What Cancers
Do We Test For?

Review the cancer types and disease subtypes across solid tumors and hematologic malignancies that are covered by GTC’s genomic testing solutions.

GTC’s Testing is comprehensive and can detect all types of cancer. This includes both solid tumors and hematologic malignancies. This is a list of common and rare types of cancers out testing detects.

Solid Tumors
Hematologic Malignancies

What Cancers Do We Test For?

Solid Tumors

Lung cancer

Subtype:
  • Non Small Cell Lung Cancer (NSCLC)
  • Squamous Cell Carcinoma
  • Large Cell Carcinoma
  • Small Cell Lung Cancer (SCLC)
  • Lung Carcinoid Tumors
  • Adenoid Cystic Carcinomas
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

GI Tumors

Subtype:
  • Adenocarcinoma
  • Gastrointestinal Stromal Tumors (GIST)
  • Carcinoid Tumors
  • Lynch Syndrome
  • Familial Adenomatous Polyposis (FAP)
  • Turcot Syndrome
  • Peutz-Jeghers Syndrome
  • MUTYH-Associated Polyposis
  • Esophageal Carcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Breast cancer

Subtype:
  • Ductal Carcinoma
  • Invasive Ductal Carcinoma
  • Lobular Carcinoma
  • Invasive Lobular Cancer
  • Triple Negative Breast Cancer (TNBC)
  • Inflammatory Breast Cancer
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Pancreatic

Subtype:
  • Adenocarcinoma
  • Cystic Tumors
  • Acinar Cell Cancers
  • Ampullary Cancers
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Sarcoma

Subtype:
  • Alveolar Soft Part Sarcoma (ASPS)
  • Angiosarcoma
  • Chondrosarcoma
  • Dermatofibrosarcoma Protuberans (DFSP)
  • Desmoid Sarcoma
  • Ewing’s Sarcoma
  • Fibrosarcoma
  • Gastrointestinal Stromal Tumor (GIST)
  • Non-Uterine leiomyosarcoma
  • Uterine leiomyosarcoma
  • Liposarcoma
  • Undifferentiated Pleomorphic Sarcoma (UPS)
  • Malignant Peripheral Nerve Sheath Tumor (MPNST)
  • Osteosarcoma
  • Rhabdomyosarcoma
  • Synovial Sarcoma
  • Leiomyosarcoma
  • Hemangiosarcoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Liver Cancer

Subtype:
  • Hepatocellular carcinoma
  • Cholangiocarcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Brain tumors

Subtype:
  • Glioblastoma
  • Meningioma
  • Craniopharyngiomas
  • Germinoma
  • Pineal region tumors
  • Medulloblastomas
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Gallbladder/ Bile Duct

Subtype:
  • Adenocarcinomas
  • Papillary adenocarcinoma
  • Adenosquamous carcinomas
  • Squamous cell carcinomas
  • Small cell carcinomas
  • Klatskin tumors
  • Intrahepatic bile duct cancer
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Stomach Cancer

Subtype:
  • Gastrointestinal stromal tumors (GIST)
  • Carcinoid tumors
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Gynecologic Cancers

Subtype:
  • Endometrial cancer
  • Serous adenocarcinoma
  • Adenosquamous carcinoma
  • Epithelial Tumors
  • Germ Cell Tumors
  • Stromal Tumors
  • Primary Peritoneal Carcinoma
  • Squamous cell carcinomas
  • Adenocarcinomas
  • Adenosquamous Carcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Cervical Cancer

Subtype:
  • Squamous cell carcinomas
  • Adenocarcinomas
  • Adenosquamous Carcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Pediatric Cancers

Subtype:
  • Neuroblastoma
  • Leukemias
  • Wilms tumor
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Melanoma

Subtype:
  • Superficial spreading melanoma
  • Nodular melanoma
  • Lentigo maligna melanoma
  • Acral lentiginous melanoma
  • Amelanotic melanoma
  • Nevoid melanoma
  • Spitzoid melanoma
  • Desmoplastic melanoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Skin cancer

Subtype:
  • Basal cell carcinoma (BCC)
  • Squamous cell carcinoma (SCC)
  • Cutaneous T-cell lymphoma
  • Dermatofibrosarcoma protuberans (DFSP)
  • Merkel cell carcinoma
  • Sebaceous carcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Prostate cancer

Subtype:
  • Neuroendocrine tumors
  • Transitional cell carcinoma
  • Prostatic ductal adenocarcinoma
  • Acinar adenocarcinoma
  • Small cell carcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Urothelial tumors / Bladder Cancer

Subtype:
  • Urothelial carcinoma
  • Squamous cell carcinoma
  • Adenocarcinoma
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Kidney Cancer

Subtype:
  • Renal cell carcinoma
  • Wilms tumor
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Head and Neck Cancers

Subtype:
  • Oropharyngeal cancer
  • Hypopharyngeal cancer
  • Laryngeal cancer
  • Lip and oral cavity cancer
  • Nasopharyngeal cancer
  • Paranasal sinus and nasal cavity cancer
  • Salivary gland cancer
  • Squamous cell neck cancer
  • Thyroid cancer
Recommended Test:

1) Solid Tumor Profile PLUS™ (FFPE block or unstained slides)
2) Liquid Trace® Solid Tumor (Peripheral blood/cfDNA/cfRNA)

Hematologic Malignancies

Lymphoma

Subtype:
  • Diffuse Large B-cell Lymphoma (DLBCL)
  • Follicular Lymphoma
  • Cutaneous T-cell Lymphoma
  • Small Cell Lymphocytic Lymphoma
  • Marginal Zone Lymphoma
  • Mucosa Associated Lymphoid Tissue Lymphoma
  • Nodal Marginal Zone Lymphoma
  • Splenic Marginal Zone Lymphomas
  • Waldenstrom Macroglobulinemia
  • AIDS-Related Lymphoma
  • Burkitt Lymphoma
  • Burkitt-like Lymphoma
  • Central Nervous System Lymphoma
  • Lymphoblastic Lymphoma
  • Mantle Cell Lymphoma
  • Composite Lymphoma
  • Hodgkin Lymphoma
  • T-cell Lymphoma
  • ALK positive/ALK Negative Lymphoma
  • NK-cell Lymphoma
  • Lymphoplasmacytic Lymphoma
Recommended Test:

1) Hematology Profile PLUS™ (Lymph node, fresh tissue, bone marrow and peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

Lymphoma

Subtype:
  • Diffuse Large B-cell Lymphoma (DLBCL)
  • Follicular Lymphoma
  • Cutaneous T-cell Lymphoma
  • Small Cell Lymphocytic Lymphoma
  • Marginal Zone Lymphoma
  • Mucosa Associated Lymphoid Tissue Lymphoma
  • Nodal Marginal Zone Lymphoma
  • Splenic Marginal Zone Lymphomas
  • Waldenstrom Macroglobulinemia
  • AIDS-Related Lymphoma
  • Burkitt Lymphoma
  • Burkitt-like Lymphoma
  • Central Nervous System Lymphoma
  • Lymphoblastic Lymphoma
  • Mantle Cell Lymphoma
  • Composite Lymphoma
  • Hodgkin Lymphoma
  • T-cell Lymphoma
  • ALK positive/ALK Negative Lymphoma
  • NK-cell Lymphoma
  • Lymphoplasmacytic Lymphoma
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

Multiple Myeloma

Subtype:
  • Non-secretory Myeloma
  • Solitary Plasmacytoma
  • Extramedullary Plasmacytoma
  • Monoclonal Gammopathy of Undetermined Significance (MGUS)
  • Smoldering Multiple Myeloma (SMM)
  • Immunoglobulin D (IgD) Myeloma
  • Immunoglobulin E (IgE) Myeloma
  • Lymphoplasmacytic Lymphoma
  • IgG4 plasma cell myeloma
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

MDS

Subtype:
  • MDS with multilineage dysplasia (MDS-MLD)
  • MDS with single lineage dysplasia (MDS-SLD)
  • MDS with ring sideroblasts (MDS-RS)
  • MDS with excess blasts (MDS-EB)
  • MDS with isolated del(5q)
  • MDS, unclassifiable (MDS-U)
  • Atypical chronic myeloid leukemia
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

Leukemia

Subtype:
  • Clonal hematopoiesis of indeterminate potential (CHIP)
  • Acute lymphocytic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic lymphocytic leukemia (CLL)
  • Chronic myeloid leukemia (CML)
  • Hairy cell leukemia (HCL)
  • Chronic myelomonocytic leukemia
  • Myeloid sarcoma
  • Acute leukemia with ambiguous lineage
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

Myeloproliferative neoplasms

Subtype:
  • Myelofibrosis
  • Polycythemia vera
  • Mastocytosis
  • Chronic myelomonocytic leukemia
  • Chronic neutrophilic leukemia
  • Essential thrombocythemia
  • Myeloid/lymphoid with PDGFRA rearrangement
  • Myeloid/lymphoid with PDGFRB rearrangement
  • Myeloid/lymphoid with FGFR1 rearrangement
  • Myeloid/lymphoid with PCM1-JAK2 rearrangement
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

Myeloproliferative neoplasms

Subtype:
  • Histiocytic sarcoma
  • Follicular dendritic cell sarcoma
  • Langerhans histiocytosis
Recommended Test:

1) Hematology Profile PLUS™ (Bone marrow or peripheral blood)
2) Liquid Trace® Hematology (Peripheral blood/cfDNA/cfRNA)

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